Kickoff from Highmark Stadium in Orchard Park, NY is set for 7:15 p.m. ET. Buffalo is a 10-point favorite in the latest Titans vs. Bills from Caesars Sportsbook, while the over/under for total points scored is 47.5. Before making any Bills vs. Titans picks, be sure to check out the NFL predictions and betting tips from SportsLine’s Larry Hartstein. A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he developed while working for Pro Football Focus. Entering the 2022 NFL season, he is 427-344 all-time among NFL teams (plus $3,764 for $100 punters), including 394-330 against the spread. Hartstein went 68-50 ATS (58 percent) and 8-3 in money games last season with $1,552 in earnings. Additionally, Hartstein went 23-12-1 in his last 36 NFL picks involving the Titans, returning $1,007. Whoever followed him is very high. Now, Hartstein has set his sights on Titans vs. Bills and has locked down his NFL picks and predictions. You can head over to SportsLine to see his picks. Here are several NFL odds and trends for Bills vs. Titans:
Titans vs. Bills spread: Buffalo -10 Titans vs. Bills over-under: 47.5 points Money Line Titans Vs. Bills: Tennessee +360, Buffalo -480 10: Titans are 8-2 against the spread in their last 10 Monday games BUF: Bills are 4-0-1 ATS in their last five games as a favorite Titans vs. Picks Bills: See the picks at SportsLine
Because they can cover the bills
Quarterback Josh Allen is off to another fast start for Buffalo. Last week in a win over the Rams, Allen completed 26 of 31 passes (83.9 percent) for 297 yards and three touchdowns. He also rushed 10 times for 56 yards and a score. In four-plus seasons as the Bills’ QB, Allen has completed 62.6 percent of his passes and has a passer rating of 91.4. Despite two picks against Los Angeles, Allen compiled a 112 rating in Week 1. Defensively, linebacker Von Miller made his presence felt. He had three tackles for loss and two sacks last week in his Buffalo debut. It was his 21st career game with two or more sacks, fourth most among active players. In four career games against Tennessee, Miller has 2.5 sacks and two forced fumbles. Miller had 9.5 sacks in 2021 while spending time in Denver and the Los Angeles Rams. He has 117.5 career sacks.
Because the Titans can cover
Quarterback Ryan Tannehill was solid in the loss to the Giants in Week 1. He completed 20 of 33 passes (60.6 percent) for 266 yards and two touchdowns for a 106.4 rating. Tannehill is coming off a season in which he completed 67.2 percent of his passes, completing 357 of 531 attempts for 3,734 yards and 21 touchdowns. He was intercepted 14 times and had an 89.6 rating. The previous year he had a 106.5 rating with 33 touchdowns and seven picks. Defensively, the Titans are stout. Last week, defensive tackle Jeffery Simmons recorded two sacks and his second career forced fumble. It was also his third game with two or more sacks. In Tennessee’s last meeting with Buffalo last October, Simmons had a sack in a 34-31 Titans win. For his career, Simmons has 141 tackles, including 88 solo, with two forced fumbles, three fumble recoveries, 15.5 sacks and 12 pass breakups.
How to make Bills vs. Titans
Hartstein has analyzed this matchup from every angle, and while we can tell you he’s leaning over the whole, he’s discovered a critical X-factor that makes him jump all over one side of the spread. He just shares what it is and who to support, on SportsLine. So who wins Bills vs. Titans on Monday Night Football? And what critical X-factor makes one side of the spread necessary? Visit SportsLine now to see which side of the Bills vs. Titans spread on the back, all from the NFL expert who is 23-12 in picks involving Tennessee, and find out.